Design considerations for murine retinal imaging using scattering angle resolved optical coherence tomography
Optical coherence tomography (OCT), an optical imaging approach enabling cross-sectional analysis of turbid samples, is routinely used for retinal imaging in human and animal models of diseases affecting the retina. Scattering angle resolved (SAR-)OCT has previously been demonstrated as offering additional contrast in human studies, but no SAR-OCT system has [...]
The impact of online discussions on the accuracy of the written output of bahraini l2 university students
[No abstract available]
Stimuli-responsive peptide-based biomaterials as drug delivery systems
Stimuli-responsive proteins have gained a wide spread interest as functional biomaterials in drug delivery area. However, particular attention has been diverted to peptide-based materials due to their adaptability and reliable practical utility in biomedical applications under a range of physiological situations. Peptides exhibit a high degree of chemical and biophysical [...]
Viscoelasticity, mechanical properties, and in vitro biodegradation of injectable chitosan-poly(3-hydroxybutyrate-co-3-hydroxyvalerate)/nanohydroxyapatite composite hydrogel
A novel injectable composite hydrogel based on chitosan and poly(3-hydroxybutyrate-co-3-hydroxyvalerate) reinforced with nanohydroxyapatite particles was synthesized. The chemical structure and morphology of the composite hydrogel were characterized. The composite hydrogel porosity, swelling, mechanical properties, viscoelasticity and in vitro biodegradation were also examined. Compared with the non-reinforced hydrogel, the composite hydrogel [...]
In silico identification of immunodominant B-cell and T-cell epitopes of non-structural proteins of Usutu Virus
Usutu Virus (USUV; flavivirus) is a re-emerging pathogen invading the territories of European countries, Asia, and Africa. It is a mosquito-borne zoonotic virus with a bi-directional transmission route from animal to human and vice versa, and causes neurological disorders such as meningoencephalitis in bats, Homo sapiens, birds and horses. Due [...]
Leishmania treatment and prevention: Natural and synthesized drugs
Leishmaniasis affects over 150 million people all over the world, especially in subtropical regions. Currently used antileishmanial synthesized drugs are associated with some drawbacks such as resistance and cytotoxicity, which hamper the chances of treatment. Furthermore, effective leishmanial vaccines are not well developed. Promising chemotherapy, either from natural or synthetic [...]
Knowledge of health professional students on waterpipe tobacco smoking: Curricula implications
Background: Tobacco prevention research traditionally focuses upon cigarette smoking, but there is also a need to implement and evaluate the usefulness of waterpipe tobacco smoking (WTS) interventions since it is considered less harmful than cigarettes. This study aimed to assess the impact of an educational intervention on WTS knowledge of [...]
2-methylpyridinium based surfactants: Synthesis, characterization and potential application as drug carrier systems
New cationic surfactants i.e., n-hexyl-2-methylpyridium bromide (a6), n-heptyl-2-methylpyridium bromide (a7) and n-octyl-2-methylpyridium bromide (a8) have been synthesized and characterized by multinuclear (1H,13C) Nuclear magnetic resonance (NMR) and Fourier-transform infrared spectroscopy (FTIR) spectroscopy. Critical micelle concentration (CMC) values of these compounds were studied in ethanol using conductometric and UV-Visible spectroscopic methods. [...]
Metal nanoparticles fabricated by green chemistry using natural extracts: Biosynthesis, mechanisms, and applications
Nanoparticles (NPs) are new inspiring clinical targets that have emerged from persistent efforts with unique properties and diverse applications. However, the main methods currently utilized in their production are not environmentally friendly. With the aim of promoting a green approach for the synthesis of NPs, this review describes eco-friendly methods [...]
Development of a highly sensitive electrochemical sensing platform for the trace level detection of lead ions
Herein we report for the first time a highly sensitive electrochemical platform for the trace level detection of Pb (ӏӏ) using glassy carbon electrode modified with 1-dodecanoyl-3-phenylthiourea (DPT). The performance of the designed sensor was tested by electrochemical impedance spectroscopy, chronocoulometry, cyclic voltammetry and Square Wave Anodic Stripping Voltammetry (SWASV). [...]