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Synthesis, in silico experiments and biological evaluation of 1,3,4-trisubstituted pyrazole derivatives as antimalarial agents

Authors: Bekhit A.A., Saudi M.N., Hassan A.M.M., Fahmy S.M., Ibrahim T.M., Ghareeb D., El-Seidy A.M., Nasralla S.N., Bekhit A.E.-D.A.
New 1,3,4-trisubstituted pyrazole derivatives were synthesized and evaluated for their antiplasmodial activity. Compounds 4b, 4c, 7a and 7d were the most potent antiplasmodial agents against P. berghei with percent of suppression ranging from 90 to 100%. They were also screened for their in vitro antimalarial activity against the chloroquine resistant [...]

Efficacy of bergamot: From anti-inflammatory and anti-oxidative mechanisms to clinical applications as preventive agent for cardiovascular morbidity, skin diseases, and mood alterations

Authors: Perna S., Spadaccini D., Botteri L., Girometta C., Riva A., Allegrini P., Petrangolini G., Infantino V., Rondanelli M.
We summarize the effects of bergamot (extract, juice, essential oil, and polyphenolic fraction) on cardiovascular, bone, inflammatory, skin diseases, mood alteration, anxiety, pain, and stress. This review included a total of 31 studies (20 studies on humans with 1709 subjects and 11 in animals (rats and mice)). In humans, bergamot-derived [...]

Impact of Heterogeneous Clusters to Implement Parallel Processing

Authors: Al-Khalidy M.M.M., Ahmed M.J., Ahmad A.J., Alghoul A.M., Khader I.M.
With the increase of the technological advancements for the last couple of years, the world has been turned to digital and it is currently directed to be an automated future, this is the fourth industrial revolution. Most of the devices have processors to process the data. Since these processors work [...]

Fabrication and characterization of nanostructured MgO·Fe2O3 composite by mechanical milling as efficient adsorbent of heavy metals

Authors: Bououdina M., Alwqyan T.S., Khezami L., Al-Najar B., Shaikh M.N., Gill R., Modwi A., Taha K.K., Lemine O.M.
Nanocrystalline magnesium ferrite is synthesized by high-energy ball milling of α-Fe2O3 and MgO powders and annealed at 700, 800 and 900 °C temperatures. The Prolonged mechanical milling process has reduced the average crystallite size of MgFe2O4 to the nanometer range as confirmed by the X-ray diffraction analysis. Along with MgFe2O4 [...]

The associations between audit firm attributes and audit quality-specific indicators: A meta-analysis

Authors: Alareeni B.A.
Purpose: This study aims to investigate the associations between audit firm attributes (i.e. audit firm size, non-audit services, auditor industry specialization and auditor-client tenure) and specific indicators of audit quality. It also aims to test whether these relationships are moderated by a set of other factors like legal system and [...]

Investigating the barriers to change management in public sector educational institutions

Authors: Al-Alawi A.I., Abdulmohsen M., Al-Malki F.M., Mehrotra A.
Purpose: The purpose of this paper is to explore barriers to the change management in the public sector of educational institutions such as public schools of the Ministry of Education in the GCC countries. The exploration of the research is based on the ADKAR change management model that consists of [...]

Safety mapping for the transportation of raw sewage by trucks in Bahrain

Authors: Qambar F.H., Elkanzi E.M., Suliman S.M.A.
As the Kingdom of Bahrain’s population and development expand, sewage transport outside the national sewer network becomes an ever increasing requirement. Due to the risk associated with sewage transport, an evaluation of industry safety practices has become necessary. Four main factors were selected to make a comprehensive safety assessment model, [...]

Attitudes and opinions towards public littering in the Kingdom of Bahrain

Authors: Freije A.M., Naser H.A., Abdulla K.H.
Public littering is widely recognized as an ongoing global problem with several implications on human health and the integrity of the environment. Waste management is one of the main challenges to sustainable development in the Arabian Gulf countries. Identifying factors that influence littering behaviour is critical for designing effective strategies [...]

Biosensors for on-line water quality monitoring–a review

Authors: Hossain S.M.Z., Mansour N.
Biosensors are analytical tools that convert a bio-signal into a measurable response. The applicability of these devices is rapidly expanding and their fabrication for continuous and real-time detection is gaining increased attention. Current research continues to further improve their features. Some of the major advantages of these devices are that [...]

Determining the optical properties of blood using He-Ne laser and double integrating sphere set-up

Authors: Ashoor H.E., Jasim K.E.
The behaviour of light interaction with biological tissue is determined by micro-optical parameters: refractive index (n), absorption coefficient (μa), scattering coefficient (μs), and anisotropy (g). The goal of this study is to measure the optical properties of normal whole blood using He-Ne laser (wavelength 632.8 nm). The refractive index is [...]
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