Authors: Bekhit A.E.-D.A., Cheng V.J., Zhang H., Mros S., Mohamed Ahmed I.A., Al-Juhaimi F.Y., Bekhit A.A., McConnell M.
Author Affiliations: Bekhit, A.E.-D.A., Department of Food Science, University of Otago, PO Box 56, Dunedin, New Zealand; Cheng, V.J., Department of Food Science, University of Otago, PO Box 56, Dunedin, New Zealand; Zhang, H., Department of Food Science, University of Otago, PO Box 56, Dunedin, New Zealand; Mros, S., Department of Microbiology and Immunology, University of Otago, PO Box 56, Dunedin, New Zealand; Mohamed Ahmed, I.A., Department of Food Science and Nutrition, College of Food and Agricultural Sciences, King Saud University, Riyadh, Saudi Arabia; Al-Juhaimi, F.Y., Department of Food Science and Nutrition, College of Food and Agricultural Sciences, King Saud University, Riyadh, Saudi Arabia; Bekhit, A.A., Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Alexandria University, Alexandria, 21521, Egypt, Pharmacy Program, Allied Health Department, College of Health Sciences, University of Bahrain32038, Bahrain; McConnell, M., Department of Microbiology and Immunology, University of Otago, PO Box 56, Dunedin, New Zealand
Publication Date: 2019
The effects of extraction process using three different solvents [50% aqueous acetone (Ace/w), 50% aqueous ethanol (Eth/w) or 50% aqueous methanol (Meth/w)] and wine production residue (seeds, skin and pomace) from Pinot noir [PN] and Pinot meunier [PM] on the phenolic profile and anti-influenza activity of their extracts were determined. Meth/w extracts resulted in the lowest (P < 0.05) total phenolic content (TPC) of seed extracts compared to other solvents, but the solvent extraction systems did not have an effect on TPC of pomace and grape skin. Pinot meunier pomace extracts had protective effects against influenza virus A at a concentration of 1 mg/mL whereas both seed and skin extracts were effective at 10 mg/mL. Meth/w extracts exhibited generally higher anti-influenza activity than other extracts. The anti-influenza activity of wine production residue extracts is not dependent on TPC. © 2018 Elsevier Ltd
Eshan2020-11-28T18:19:12+00:00
