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Polyphenol uses in biomaterials engineering

Authors: Shavandi A., Bekhit A.E.-D.A., Saeedi P., Izadifar Z., Bekhit A.A., Khademhosseini A.
Polyphenols are micronutrients obtained from diet that have been suggested to play an important role in health. The health benefits of polyphenols and their protective effects in food systems as antioxidant compounds are well known and have been extensively investigated. However, their functional roles as a “processing cofactor” in tissue [...]

Folate conjugated vs PEGylated phytosomal casein nanocarriers for codelivery of fungal-and herbal-derived anticancer drugs

Authors: El-Far S.W., Helmy M.W., Khattab S.N., Bekhit A.A., Hussein A.A., Elzoghby A.O.
Aim: Monascin and ankaflavin, the major fractions of the fungal-derived monascus yellow pigments, were incorporated with the herbal drug, resveratrol (RSV) within the core of folate-conjugated casein micelles (FA-CAS MCs, F1) for active targeting. PEGylated RSV-phospholipid complex bilayer enveloping casein-loaded micelles (PEGPC-CAS MCs) were also developed as passive-Targeted nanosystem. Results: [...]

Carbamazepine coated silver nanoparticles for the simultaneous electrochemical sensing of specific food toxins

Authors: Shah A., Malik M.S., Zahid A., Iftikhar F.J., Anwar A., Akhter M.S., Shah M.R., Zia M.A., Ashiq M.N., Shah A.H.
Monitoring the use of colored additives in food commodities due to their potential carcinogenic effects is important for regulating their safe use. Herein, we test the cytotoxicity of food dyes against human neuroblastoma cell (SH-SY5Y) and report the development and applications of a novel and sensitive electrochemical sensor based on [...]

Anti-leishmanial click modifiable thiosemicarbazones: Design, synthesis, biological evaluation and in silico studies

Authors: Temraz M.G., Elzahhar P.A., El-Din A. Bekhit A., Bekhit A.A., Labib H.F., Belal A.S.F.
Leishmaniasis is a devastating tropical disease with limited therapeutic options. Depending on recently reported active anti-leishmanial compounds, we designed and synthesized a series of click modifiable 1,2,3-triazole and thiosemicarbazone hybrids. Most of the synthesized compounds showed comparable to superior activity to a well-established anti-leishmanial drug miltefosine. Compounds 2 and 10a [...]

Spatial distribution and source apportionment of air pollution in Bahrain using multivariate analysis methods

Authors: Jassim M.S., Coskuner G., Marzooq H., AlAsfoor A., Taki A.A.
The objective of this study is to identify the most important air pollutants based on their individual contribution to Air Quality Index (AQI) and to determine the major air pollution sources in Bahrain. Data sets from seventeen air quality monitoring sites were evaluated using XLSTAT 2014 and Statistical Package for [...]

A framework for an artificial-neural-network-based electronic nose

Authors: Ismail M., Abdul A., Albastaki Y.
Machine odor detection has developed into an important aspect of our lives with various applications of it. From detecting food spoilage to diagnosis of diseases, it has been developed and tested in various fields and industries for specific purposes. This project, artificial-neural-network-based electronic nose (ANNeNose), is a machine-learning-based e-nose system [...]

Conventional and microwave combustion synthesis of optomagnetic CuFe2O4 nanoparticles for hyperthermia studies

Authors: Kombaiah K., Vijaya J.J., Kennedy L.J., Bououdina M., Al-Najar B.
Nanosized copper ferrite (CuFe2O4) nanoparticles have been prepared by conventional (CCM) and microwave (MCM) combustion methods using Hibiscus rosa sinensis plant extract as a fuel. XRD and rietveld analysis confirmed the formation of single cubic phase and with crystallite size varying from 25 to 62 nm owing to grain growth [...]

Impact of life-style on health and physical capability: A data mining approach

Authors: Zeki A.M., Ramadan A.M., Zeb F.K., Ibrahim M.
In this paper1, the impact of life-style habits (behavioral including sleep, eating, body type, physical activities and health condition) on an individual’s health in terms of physical capabilities is studied using data mining techniques. The study aims at finding and recommending the best life-style habits that will help an individual [...]

Heteroleptic Palladium(II) dithiocarbamates: Synthesis, characterization and in vitro biological screening

Authors: Khan S.Z., Zia-ur-Rehman, Amir M.K., Ullah I., Akhter M.S., Bélanger-Gariepy F.
Two new heteroleptic Pd(II) complexes of sodium 4-(2-pyrimidyl)piperazine-1-carbodithioate with tris-p-flourophenylphosphine (1) and tris-p-chlorophenylphosphine (2) were prepared and characterized by elemental analysis, FT-IR, multinuclear NMR {1H, 13C and 31P} and single-crystal X-ray diffraction measurement. In both complexes, Pd exhibit pseudo square planner geometry mediated by SS chelate, P and Cl. In [...]

Bioengineered intravaginal isolate of Lactobacillus plantarum expresses algal lectin scytovirin demonstrating anti-HIV-1 activity

Authors: Janahi E.M.A., Haque S., Akhter N., Wahid M., Jawed A., Mandal R.K., Lohani M., Areeshi M.Y., Almalki S., Das S., Dar S.A.
Efforts to develop preventatives against HIV infection through sexual route have identified, among many, algal lectins as the potent molecules for scaffolding HIV entry inhibition. Algal lectin scytovirin (SVN) from Scytonema varium, a cyanobacterium, has anti-HIV effects with the potential for use in sculpting HIV neutralization. We created a recombinant [...]
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